Project Report For Curcumin Extraction

Project report for Curcumin Extraction is as follows.

Curcumin, also known as diferuloylmethane, is a hydrophobic polyphenol that is obtained from the rhizome of perennial herbs in the genus Curcuma. It is produced by the ginger family (Zingiberaceae), which includes species like Curcuma longa, Curcuma amada, Curcuma zedoaria, Curcuma aromatic, and Curcuma raktakanta. 

The most popular variety of this species is turmeric. Curcumin (75%), demethoxycurcumin (10%-20%), and bisdemethoxycurcumin (5%), the most significant bioactive compound, are the three curcuminoid derivatives that are typically found in 3-5% of turmeric rhizomes. 

Curcumin has a long history of use in Indian curries as a spice and natural coloring agent in addition to being an active component in traditional Chinese medicine. The human immune system is essential to our body’s protection against external threats, such as cancer, and pathogenic bacteria.

A person with a compromised immune system is more vulnerable to diseases brought on by pathogens such as bacteria, viruses, parasites, and fungi.

Curcumin can be obtained in two ways: synthetically and by extracting it from plants. The process of creating synthetic curcumin has been detailed by numerous publications. The most cost-effective method for producing curcumin, however, remains extracting the naturally occurring curcumin found in plants. 

The quantity and quality of bioactive chemicals are said to be highly dependent on the extraction process. It is crucial to select suitable and efficient processes and carry them out under ideal circumstances in order to produce high-yield and high-quality curcumin.

Curcumin is subjected to additional separation and purification steps following successful extraction using various techniques. A number of purifying techniques, such as column chromatography, semi-preparative high performance liquid chromatography, high-speed counter-current chromatography, preparative supercritical fluid chromatography, and crystallisation, have been developed for isolation and purification based on variables like polarity, ligand interaction, and solubility.

The use of curcumin in conventional medicine is widespread. Its demand has grown recently in the culinary, cosmetic, and pharmaceutical sectors. Many studies have looked into the uses of curcumin in food, medicine, cosmetics, and health products.

Curcumin’s structure (C 21 H 20 O 6) was discovered to be diferuloylmethane by Lampe and Milobedeska in 1910. Turmeric is used as a spice, a colouring ingredient in foods and textiles, and a therapy for a range of diseases. In traditional Indian medicine, it is commonly used to treat biliary diseases, anorexia, cough, diabetic wounds, hepatic problems, rheumatism, and sinusitis.